Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Vcan  versican   (Synonyms: 5430420N07Rik, Cspg2, DPEAAE, hdf, heart defect, PG-M)
Results	Reference
1*	J:316301 Asano K, Nelson CM, Nandadasa S, Aramaki-Hattori N, Lindner DJ, Alban T, Inagaki J, Ohtsuki T, Oohashi T, Apte SS, Hirohata S, Stromal Versican Regulates Tumor Growth by Promoting Angiogenesis. Sci Rep. 2017 Dec 8;7(1):17225
1	J:213297 Briggs LE, Phelps AL, Brown E, Kakarla J, Anderson RH, van den Hoff MJ, Wessels A, Expression of the BMP receptor Alk3 in the second heart field is essential for development of the dorsal mesenchymal protrusion and atrioventricular septation. Circ Res. 2013 May 24;112(11):1420-32
1	J:179734 Cooley MA, Fresco VM, Dorlon ME, Twal WO, Lee NV, Barth JL, Kern CB, Iruela-Arispe ML, Argraves WS, Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation. Dev Dyn. 2012 Feb;241(2):303-14
1	J:166902 Enomoto H, Nelson CM, Somerville RP, Mielke K, Dixon LJ, Powell K, Apte SS, Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation. Development. 2010 Dec;137(23):4029-38
1*	J:49941 Henderson DJ, Copp AJ, Versican expression is associated with chamber specification, septation, and valvulogenesis in the developing mouse heart. Circ Res. 1998 Sep 7;83(5):523-32
1	J:183686 Lin CY, Lin CJ, Chen CH, Chen RM, Zhou B, Chang CP, The secondary heart field is a new site of calcineurin/Nfatc1 signaling for semilunar valve development. J Mol Cell Cardiol. 2012 May;52(5):1096-102
1	J:136358 Mecha M, Rabadan MA, Pena-Melian A, Valencia M, Mondejar T, Blanco MJ, Expression of TGF-betas in the embryonic nervous system: analysis of interbalance between isoforms. Dev Dyn. 2008 Jun;237(6):1709-17
1*	J:249183 Saxon JG, Baer DR, Barton JA, Hawkins T, Wu B, Trusk TC, Harris SE, Zhou B, Mishina Y, Sugi Y, BMP2 expression in the endocardial lineage is required for AV endocardial cushion maturation and remodeling. Dev Biol. 2017 Oct 1;430(1):113-128
1	J:338019 Shi W, Scialdone AP, Emerson JI, Mei L, Wasson LK, Davies HA, Seidman CE, Seidman JG, Cook JG, Conlon FL, Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1. Circ Res. 2023 Jun 23;133(1):48-67
1*	J:86321 Shibata S, Fukada K, Imai H, Abe T, Yamashita Y, In situ hybridization and immunohistochemistry of versican, aggrecan and link protein, and histochemistry of hyaluronan in the developing mouse limb bud cartilage. J Anat. 2003 Oct;203(4):425-32
1*	J:227082 Snyder JM, Washington IM, Birkland T, Chang MY, Frevert CW, Correlation of Versican Expression, Accumulation, and Degradation during Embryonic Development by Quantitative Immunohistochemistry. J Histochem Cytochem. 2015 Dec;63(12):952-67
1*	J:302455 Stupka N, Kintakas C, White JD, Fraser FW, Hanciu M, Aramaki-Hattori N, Martin S, Coles C, Collier F, Ward AC, Apte SS, McCulloch DR, Versican processing by a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats proteinases-5 and -15 facilitates myoblast fusion. J Biol Chem. 2013 Jan 18;288(3):1907-17
1	J:243646 Toomer KA, Fulmer D, Guo L, Drohan A, Peterson N, Swanson P, Brooks B, Mukherjee R, Body S, Lipschutz JH, Wessels A, Norris RA, A role for primary cilia in aortic valve development and disease. Dev Dyn. 2017 Aug;246(8):625-634
1	J:341382 Wu B, Wu B, Benkaci S, Shi L, Lu P, Park T, Morrow BE, Wang Y, Zhou B, Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development. J Am Heart Assoc. 2023 Sep 19;12(18):e029683
1*	J:277788 Xu F, Cai W, Chen W, Li L, Li X, Jiang B, Expression of Different Isoforms of Versican During the Development of Mouse Mandibular First Molars. J Histochem Cytochem. 2019 Jul;67(7):471-480
1	J:287549 Xu J, Liu H, Lan Y, Park JS, Jiang R, Genome-wide Identification of Foxf2 Target Genes in Palate Development. J Dent Res. 2020 Apr;99(4):463-471